Recent mitigation strategies in engineered healthcare materials towards antimicrobial applications. (June 2022)

• Record Type: Journal Article
• Authors: Vijayan, Vineeth M.; Walker, Melissa; Morris, J. Jeff; Thomas, Vinoy
• Is Part Of: Current opinion in biomedical engineering. Volume 22(2022)
• Publication Date: 2022-06
• Subjects: Antifouling surfaces -- Engineered materials -- Surface properties -- Biomedical implants; Gold Nanoparticles AuNp -- Silver Nanoparticles AgNp -- Quorum sensing QS -- Antimicrobial Peptides AMP -- Reactive oxygen species ROS -- Antimicrobial peptides AMPs -- Polycaprolactone PCL; Biomedical engineering -- Periodicals; 610.28
• DOI: 10.1016/j.cobme.2022.100377
• Languages: English
• ISSNs: 2468-4511

Abstract

Abstract: The design of material surfaces with antimicrobial properties is highly relevant to the fabrication of medical devices. Biofilm formation with its subsequent infection constitutes a primary reason for device failure. Hence, it is highly relevant to design healthcare materials with antibacterial properties which can efficiently resist biofilm formation and infection. The present current opinion article attempts to give a brief overview of some more recent advances in infection mitigation strategies. A major emphasis has been placed on material science and biological perspectives of biomaterial infection and corresponding mitigation strategies to prevent infection.