Case Report: successful use of phage therapy in refractory MRSA chronic rhinosinusitis. (August 2022)

• Record Type: Journal Article
• Authors: Rodriguez, J. Martin; Woodworth, Bradford A; Horne, Bri'Anna; Fackler, Joseph; Brownstein, Michael J.
• Is Part Of: International journal of infectious diseases. Volume 121(2022)
• Page Start: 14
• Page End: 16
• Publication Date: 2022-08
• Subjects: Bacteriophage -- Phage -- Chronic rhinosinusitis -- Staphylococcus aureus; Communicable diseases -- Periodicals; Communicable Diseases -- Periodicals; Communicable diseases; Periodicals; Electronic journals; 616.9
• DOI: 10.1016/j.ijid.2022.04.049
• Languages: English
• ISSNs: 1201-9712

Abstract

Highlights: Chronic rhinosinusitis can be very difficult to treat. Many patients have recurrent infections for years. Antibiotics and surgery sometimes are not enough to cure the patient. Phage therapy is a promising approach for difficult-to-treat infections. Abstract: We present a case of refractory methicillin-resistant Staphylococcus aureus that was successfully treated with a combination of antibiotics, systemic phage and intranasal phage therapy.