Cerium(III) triflate–catalyzed cycloaddition reaction in aqueous conditions to substituted naphthotriazolediones. Issue 5 (14th May 2022)

• Record Type: Journal Article
• Authors: Li, Ya‐Syuan; Liang, Chien‐Fu
• Is Part Of: Journal of the Chinese Chemical Society. Volume 69:Issue 5(2022)
• Page Start: 849
• Page End: 855
• Publication Date: 2022-05-14
• Subjects: 1, 2, 3‐triazole -- 1, 4‐naphthoquinone -- cerium(III) triflate -- cycloaddition -- naphthotriazolediones; Chemistry -- Periodicals; Electronic journals; 540.5
• DOI: 10.1002/jccs.202200018
• Languages: English
• ISSNs: 0009-4536

Abstract

Abstract: In this study, the cerium(III) trifluoromethanesulfonate–catalyzed cycloaddition of 1, 4‐naphthoquinone with functionalized azides in aqueous solutions was used to synthesize naphtho[2, 3‐ d ][1, 2, 3]triazole‐4, 9‐dione derivatives. Moreover, our method boasts scalability and completes the synthesis of two key biological compounds. Our method's advantages are environmentally friendly reaction conditions, easy applicability in large‐scale operations, broad structurally diverse products produced in high yields, and the recyclability of catalysts. Abstract : This strategy involves the use of cerium(III) triflate‐catalyzed cycloaddition of 1, 4‐naphthoquinone with diverse functionalized azides in aqueous solutions. Moreover, the proposed method overcomes the limitations of conventional methods by using water compatibility catalyst, and the reusability of it was examined for consecutive cycles.