Pilocytic astrocytoma with spontaneous malignant transformation with intracranial and skeletal dissemination: case report and review of the literature. (2nd January 2022)

• Record Type: Journal Article
• Authors: Konar, Subhas K.; Nandeesh, B. N.; Sandhya, M.; Chandana, N.; Devi, B. Indira; Bhat, Dhananjaya I.
• Is Part Of: British journal of neurosurgery. Volume 36:Number 1(2022)
• Page Start: 90
• Page End: 93
• Publication Date: 2022-01-02
• Subjects: Pilocytic astrocytoma -- malignant transformation -- skeletal metastasis -- outcome; Nervous system -- Surgery -- Periodicals; 617.48
• DOI: 10.1080/02688697.2018.1472214
• Languages: English
• ISSNs: 0268-8697

Abstract

Abstract: Pilocytic astrocytoma is a benign low-grade tumor with a favorable prognosis. We present a 47-year-old- lady with a posterior fossa pilocytic astrocytoma who underwent surgical decompression. She developed multiple early local recurrences Along with malignant transformation of the cranial lesion she developed skeletal dissemination within a very short time frame. There were no features or family history of neurofibromatosis 1. She did not receive radiotherapy or chemotherapy prior to the recurrences.