Association of Epidural Analgesia During L&D With Autism Spectrum Disorder in Offspring. Issue 2 (24th June 2022)

• Record Type: Journal Article
• Authors: Hanley, G.E.; Bickford, C.; Ip, A.; Lanphear, N.; Lanphear, B.; Weikum, W.; Zwaigenbaum, L.; Oberlander, T.F.
• Is Part Of: Obstetric anesthesia digest. Volume 42:Issue 2(2022)
• Page Start: 53
• Page End: 54
• Publication Date: 2022-06-24
• Subjects: Analgesia for Labor -- Anesthetic Complications; Anesthesia in obstetrics -- Periodicals; Anesthesia in obstetrics -- Abstracts -- Periodicals; 617.968205
• DOI: 10.1097/01.aoa.0000827772.18871.ce
• Languages: English
• ISSNs: 0275-665X

Abstract

Abstract : ( JAMA . 2021;326:1178–1185) Although epidural analgesia is a common and safe modality for pain relief during labor and delivery, few studies have examined long-term outcomes. Since 2000 the diagnosis of Autism Spectrum Disorder (ASD) in children has increased from 1 in 150 to 1 in 54 in 2016 in the United States. Inconsistent and conflicting studies have suggested there may be a relationship between epidural analgesia and a later diagnosis of ASD. Considering epidural analgesia use is reported at 57% in Canada and higher than 70% in the United States, millions of newborns in both countries could be impacted. The aim of this population-based study of British Columbia, Canada evaluated the association between ASD in offspring and maternal epidural analgesia use during delivery.