Myxedema Coma Associated with Macroprolactinoma: Case Report and Review of the Literature. (28th April 2022)

• Record Type: Journal Article
• Authors: Omoniyi, Elizabeth Jasola; Robbins, Richard J.
• Other Names: Kita Toshihiro Academic Editor.
• Is Part Of: Case reports in endocrinology. Volume 2022(2022)
• Publication Date: 2022-04-28
• Subjects: Endocrinology -- Periodicals; Endocrinology -- Case studies -- Periodicals; Endocrine glands -- Diseases -- Periodicals; Endocrinology; Endocrine System Diseases; Endocrine glands -- Diseases; Endocrinology; Electronic journals; Periodicals; Case studies; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 616.4
• DOI: 10.1155/2022/1591616
• Languages: English
• ISSNs: 2090-6501

Abstract

Abstract : Myxedema coma is a rare life-threatening presentation of severe hypothyroidism associated with a high mortality rate. Although most cases are due to primary thyroid failure, a minority have central hypothyroidism as the underlying cause. We report the case of a 69-year-old man who presented with obtundation, hypoglycemia, and hyponatremia. The patient's initial thyroid-stimulating hormone (TSH) was within normal limits. Subsequent evaluation revealed critical anterior pituitary insufficiency due to a macroprolactinoma and a diagnosis of myxedema coma after appropriate workup The finding of a normal serum TSH should not eliminate the possibility of myxedema coma.