Treatment of Hepatoblastoma With Drug-eluting Bead Transarterial Chemoembolization in a 13-Month-Old Infant: A Case Report and Review of the Literature. Issue 1 (January 2021)

• Record Type: Journal Article
• Authors: Hoyer, Matthew; Goli, Rakesh; Barnett, Katherine K.; Raabe, Eric H.; Hong, Kelvin
• Is Part Of: Journal of pediatric hematology/oncology. Volume 43:Issue 1(2021)
• Publication Date: 2021-01
• Subjects: DEB-TACE -- hepatoblastoma -- interventional radiology -- interventional oncology; Pediatric hematology -- Periodicals; Tumors in children -- Periodicals; 618.9215
• DOI: 10.1097/MPH.0000000000001842
• Languages: English
• ISSNs: 1077-4114

Abstract

Abstract : Background: Prior reports have shown the utility of conventional lipiodol-based transarterial chemoembolization in hepatoblastoma. The authors describe the first reported case of hepatoblastoma treated with drug-eluting bead transarterial chemoembolization (DEB-TACE). Observations: An 11-month-old infant presented with hepatoblastoma measuring 14.3 cm. A trial of cisplatin chemotherapy followed by sequential DEB-TACE to the tumor's feeding vasculature reduced the mass to 5.3 cm. The patient tolerated both sessions of DEB-TACE without any major complication. Having demonstrated adequate disease control, the patient then underwent successful liver transplantation. Conclusion: This report provides promising evidence for the treatment of hepatoblastoma with DEB-TACE.