18F-PSMA-1007 PET/CT for Initial Staging of Renal Cell Carcinoma in an End-Stage Renal Disease Patient. (January 2021)

• Record Type: Journal Article
• Authors: Marafi, Fahad; Sasikumar, Arun; Aldaas, Mariam; Esmail, Abdulredh
• Is Part Of: Clinical nuclear medicine. Volume 46:Number 1(2021)
• Publication Date: 2021-01
• Subjects: 18F-PSMA-1007 -- PET/CT -- renal cell carcinoma -- end-stage renal disease; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000003354
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: A 46-year-old man with end-stage renal disease and renal cell carcinoma underwent 18 F-FDG PET/CT for initial staging followed by 18 F-PSMA-1007 PET/CT. Unlike 18 F-FDG, which undergoes renal clearance, 18 F-PSMA-1007 undergoes hepatobiliary clearance and thus generates superior quality images. 18 F-PSMA-1007 PET/CT showed intense tracer-avid left renal mass lesion (FDG nonavid); lytic bone lesions (FDG avid) and single liver lesion (FDG nonavid). This case highlights the superiority of 18 F-PSMA-1007 over 18 F-FDG PET/CT in identifying primary lesion as well as metastatic sites in case of renal cell carcinoma even in the presence of end-stage renal disease.