Targeting Fatigue in Stroke Patients. (30th November 2011)

• Record Type: Journal Article
• Authors: Barritt, Andrew W.; Smithard, David G.
• Other Names: Arboix A. Academic Editor.; Conti A. Academic Editor.
• Is Part Of: ISRN neurology. Volume 2011(2011)
• Publication Date: 2011-11-30
• Subjects: Neurology -- Periodicals; Nervous System Diseases; Neurology; Neurology; Periodicals; 616.8
• DOI: 10.5402/2011/805646
• Languages: English
• ISSNs: 2090-5505

Abstract

Abstract : Symptoms of fatigue are often reported by patients in both the acute and chronic stages of recovery following a stroke. It is commonly associated with low mood and sleep disturbances, but can arise in their absence. However, it has also been associated with poorer long-term outcome and, as such, its aetiology warrants a greater understanding. There is convincing evidence that inflammatory cascades and cytokine signalling precipitated by the infarct promote fatigue, and these pathways may harbour therapeutic targets in its management.