Agricultural Animals as Biomedical Models: Occupational Health and Safety Considerations. (22nd November 2018)

• Record Type: Journal Article
• Authors: Edwards, Gaylen L; Azain, Michael J; Parks, Andrew
• Is Part Of: ILAR journal. Volume 59:Number 2(2018:Jun.)
• Page Start: 161
• Page End: 167
• Publication Date: 2018-11-22
• Subjects: animal husbandry -- biomedical research -- livestock -- safety biosafety -- review; Laboratory animals -- Periodicals; Animal models in research -- United States -- Periodicals; Animal Welfare -- Periodicals; Animals, Laboratory -- Periodicals; Transplantation, Heterologous -- Periodicals; 636.0885
• DOI: 10.1093/ilar/ily013
• Languages: English
• ISSNs: 1084-2020

Abstract

Abstract: The use of agricultural animals in biomedical research is increasing. Their overall size and metabolic rate, organ size, longer gestation period, and other physiological similarities make them good candidates for animal models of human disease. There are a number of special considerations for use of traditional farm animals for biomedical research. Differences in physical plant infrastructure, handling equipment, training of personnel, and potential zoonoses are some of the important considerations when traditional farm animals are used in biomedical research. This article provides an overview of some of the special considerations for using traditional agricultural animals in biomedical research. With the growing need for improved translational research, it is reasonable to predict significant growth in these animal models.