Assessment of Resistance to Organophosphates and Pyrethroids in Aedes aegypti (Diptera: Culicidae): Do Synergists Affect Mortality?. Issue 6 (2nd June 2020)

• Record Type: Journal Article
• Authors: Cataldo, Natalie P; Lea, C Suzanne; Kelley, Timothy; Richards, Stephanie L
• Editors: Badolo, Athanase
• Is Part Of: Journal of medical entomology. Volume 57:Issue 6(2020)
• Page Start: 1992
• Page End: 1996
• Publication Date: 2020-06-02
• Subjects: Ae aegypti -- pyrethroid -- organophosphate -- Biomist -- Mosquitomist; Insects as carriers of disease -- Periodicals; 616.968
• DOI: 10.1093/jme/tjaa101
• Languages: English
• ISSNs: 0022-2585

Abstract

Abstract: Aedes aegypti (L.) is the primary vector of Zika, dengue, yellow fever, and chikungunya viruses. Insecticides used in mosquito control can help prevent the spread of vector-borne diseases. However, it is essential to determine insecticide resistance (IR) status before control measures are undertaken. Only the most effective insecticides should be used to avoid ineffective control and/or promotion of IR. Pyrethroids and organophosphates are the most commonly used insecticides for mosquito control. Here, the efficacy of two active ingredients (AIs; permethrin [pyrethroid], chlorpyrifos [organophosphate]), two formulated products (FPs; Biomist [AI: permethrin]) and (Mosquitomist [AI: chlorpyrifos]), and three synergists (piperonyl butoxide, diethyl maleate, S-S-S-tributyl phosphorotrithioate) was evaluated in two Ae. aegypti colonies (pyrethroid resistant and susceptible). Mosquitomist was most effective against the pyrethroid-resistant colony (100% mortality at diagnostic time). Pre-exposure to synergists did not increase the efficacy of AIs against the pyrethroid-resistant colony. Further research is needed to discover how synergists may affect the efficacy of insecticides when used on pyrethroid-resistant mosquitoes.