Pandemic Uropathogenic Fluoroquinolone-resistant Escherichia coli Have Enhanced Ability to Persist in the Gut and Cause Bacteriuria in Healthy Women. (4th July 2019)

• Record Type: Journal Article
• Authors: Tchesnokova, Veronika L; Rechkina, Elena; Chan, Diana; Haile, Helen Ghirmai; Larson, Lydia; Ferrier, Kendra; Schroeder, David W; Solyanik, Thalia; Shibuya, Spencer; Hansen, Kelly; Ralston, James D; Riddell, Kim; Scholes, Delia; Sokurenko, Evgeni V
• Is Part Of: Clinical infectious diseases. Volume 70:Number 5(2020)
• Page Start: 937
• Page End: 939
• Publication Date: 2019-07-04
• Subjects: gut microflora -- urinary tract infections -- Escherichia coli -- fluoroquinolone resistance -- bacteriuria; Communicable diseases -- Periodicals; 616.905
• DOI: 10.1093/cid/ciz547
• Languages: English
• ISSNs: 1058-4838

Abstract

Abstract: We report that fluoroquinolone-resistant Escherichia coli are found in feces of 8.8% of healthy women, with most bacteria belonging to pandemic multidrug-resistant ST131- H 30R or ST1193 clonal groups. Moreover, these highly uropathogenic clonal groups demonstrate an especially prolonged gut persistence and high rate of bacteriuria without documented urinary tract infection.