67 Effects of Monoglycerides on Growth Performance and Diarrhea of Weanling Pigs Experimentally Infected with a Pathogenic Escherichia coli. (12th April 2022)

• Record Type: Journal Article
• Authors: Park, Sangwoo; Kim, Kwangwook; Sokale, Adebayo O; Barri, Adriana; Liu, Yanhong
• Is Part Of: Journal of animal science. Volume 100(2022)Supplement 2
• Page Start: 25
• Page End: 26
• Publication Date: 2022-04-12
• Subjects: diarrhea -- monoglycerides -- weaned pigs; Livestock -- Periodicals; Livestock; Electronic journals; Periodicals; 636.005
• DOI: 10.1093/jas/skac064.041
• Languages: English
• ISSNs: 0021-8812

Abstract

Abstract: This study aimed to investigate the effects of monoglycerides on growth performance and diarrhea of weanling pigs experimentally infected with Escherichia coli ( E. coli ) F18. Sixty weaned pigs [body weight (BW) = 6.49 ± 0.74 kg; around 21 d old] were individually housed and fed with 1 of 4 diets (15 replicates/diet): 1) control diet (CON); 2) CON+0.3% monoglycerides; 3) CON+3000 mg/kg ZnO and 4) CON+50 mg/kg antibiotics (carbadox). The experiment lasted 28 d with 7 d before and 21 d after first inoculation (d 0). All piglets were orally challenged with F18 E. coli (10 10 CFU/3 mL) for 3 consecutive days. Growth performance was measured, and diarrhea scores were recorded daily throughout the experiment. Fecal swabs were collected on d 2, 5, 7, 10, 14, and 21 post-inoculation (PI) to estimate the percentage of β-hemolytic coliforms. Data were analyzed by ANOVA using PROC MIXED of SAS with randomized complete block design. Supplementation of ZnO increased ( P < 0.05) BW on d 5, 14, and 21 PI, and average daily gain and average daily feed intake from d 0 to 21 PI, compared with other treatments. Both monoglycerides and antibiotics did not affect growth performance throughout the experiment. Compared with CON, supplementation of ZnO or antibiotics reduced ( P < 0.05) the incidence and severity of diarrhea, while supplementation of monoglycerides tended to have less ( P < 0.10) severity of diarrhea throughout the experiment. The addition of ZnO reduced ( P < 0.05) the percentage of β-hemolytic coliforms in feces on d 5 PI compared with CON. No differences were observed in the severity of diarrhea and percentage of β-hemolytic coliforms among monoglycerides, ZnO, and antibiotics. In conclusion, dietary supplementation of 0.3% monoglycerides did not enhance growth rate but may reduce diarrhea severity of weaned pigs infected with E. coli F18.