A Cyclopalladated BODIPY Construct as a Fluorescent Probe for Carbon Monoxide. Issue 14 (27th April 2022)

• Record Type: Journal Article
• Authors: Çevik Eren, Merve; Eren, Ahmet; Dartar, Suay; Buse Tütüncü, Büşra; Emrullahoğlu, Mustafa
• Is Part Of: European journal of inorganic chemistry. Volume 2022:Issue 14(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-04-27
• Subjects: BODIPY -- Carbon monoxide -- Chemosensors -- Fluorescent probes -- Palladacycles; Chemistry, Inorganic -- Periodicals; Organometallic chemistry -- Periodicals; Bioinorganic chemistry -- Periodicals; Solid state chemistry -- Periodicals; 546
• DOI: 10.1002/ejic.202200093
• Languages: English
• ISSNs: 1434-1948

Abstract

Abstract: By introducing a palladium ion into the backbone of BODIPY, we devised a cyclopalladated BODIPY construct that was almost non‐emissive in the absence of any analyte but became highly fluorescent upon interacting with carbon monoxide (CO) in solution and in living cells. A process of ortho ‐carbonylation and depalladation mediated by the specific binding of CO to palladium, promoted the release of the heavy atom from the fluorophore and consequently generated a fluorescence signal with an exceptionally high (60‐fold) enhancement ratio. Abstract : A BODIPY‐based palladacycle displays a selective turn‐on type fluorescent response towards carbon monoxide (CO) both in solution and living systems. Following an ortho ‐carbonylation/depalladation reaction pathway mediated by the addition of CO, the non‐fluorescent dye rapidly transforms into a new structure and induces a fluorescence response clearly observable with the naked eye.