Anticancer and Antioxidant Activity of Morinda Citrifolia Leaf Mediated Selenium Nanoparticles. (11th May 2022)

• Record Type: Journal Article
• Authors: Nagalingam, M.; Rajeshkumar, S.; Balu, Satheesh Kumar; Tharani, M.; Arunachalam, Kalirajan
• Other Names: Roy Arpita Academic Editor.
• Is Part Of: Journal of nanomaterials. Volume 2022(2022)
• Publication Date: 2022-05-11
• Subjects: Nanostructured materials -- Periodicals; Nanotechnology -- Periodicals; Nanomatériaux; Nanostructured materials; Nanotechnology; Nanostructures; Nanotechnology; Periodicals; Fulltext; Internet Resources; Periodicals; 620.115
• DOI: 10.1155/2022/2155772
• Languages: English
• ISSNs: 1687-4110

Abstract

Abstract : The goal of the present work is to fabricate selenium nanoparticles utilising Morinda citrifolia leaves extract via green approach. UV-Vis spectroscopy, FT-IR, and TEM were used to characterise the green nanoparticles. The size of generated SeNPs in Morinda citrifolia was anticipated to be 12-160 nm based on TEM images. The antioxidant activity of selenium NPs was discovered to be 66.7 to 83.7% of free radical inhibtion. When the concentration of nanoparticles rises, the viability of cancer cells decreases. It shows that biosynthesized selenium nanoparticles have anticancer properties that depend on the concentration. The brine shrimp lethality assay revealed that Morinda citrifolia mediated selenium nanoparticles have low cytotoxic effects.