Biofunctional properties and plant physiology of Kaempferia spp.: Status and trends. (May 2022)

• Record Type: Journal Article
• Authors: Hashiguchi, Akiko; San Thawtar, May; Duangsodsri, Teerarat; Kusano, Miyako; Watanabe, Kazuo N.
• Is Part Of: Journal of functional foods. Volume 92(2022)
• Publication Date: 2022-05
• Subjects: Kaempferia -- Biofunctional properties -- Pharmacological action -- Physiological response -- Value-added production; AMPK 5′ adenosine monophosphate-activated protein kinase -- ATGL adipose triglyceride lipase -- Bar-HRM DNA barcoding coupled with high resolution melting -- AChE acetylcholinesterase -- BAX Bcl2 associated X -- BChE butyrylcholinesterase -- Bcl-2 B-cell/CLL lymphoma 2 -- cGMP cyclic guanosine monophosphate -- COL collagen -- COX cyclooxygenase -- CYP cytochrome P450 -- DCX doublecortin -- DGAT diglyceride acyltransferase -- DPYSL2 dihydropyrimidinase Like 2 -- EMPC ethyl-p-methoxy cinnamate -- ER endoplasmic reticulum -- ERK extracellular signal regulated kinase -- ERR estrogen-related receptor -- E2F1 transcription factor E2F1 -- FASN fatty acid synthase -- FGF fibroblast growth factor -- FOXO3 forkhead box protein O3 -- GFAP glial fibrillary acidic protein -- HSL hormone-sensitive lipase -- HUVEC human umbilical vein endothelial cells -- IFNβ interferon β -- IL-6 interleukin-6 -- ISSR inter-simple sequence repeat -- JNK c-Jun N-terminal kinase -- LPAAT Lysophosphatidic acid acyltransferase -- LYN Lck/Yes-related novel protein tyrosine kinase -- MAPK mitogen-activated protein kinase -- MCL1 myeloid leukemia cell differentiation protein MCL-1 -- MMPs matrix metalloproteinases -- NFAT-c1 nuclear factor of activated T-cells, cytoplasmic 1 -- NF-κB nuclear factor-kappa B -- NOS nitric oxide synthase -- NRF1 nuclear respiratory factor 1 -- PARP1 poly(ADP-ribose)polymerase 1 -- PDE5 cGMP-specific phosphodiesterase type 5 -- PDIA3 rotein disulfide-isomerase A3 -- PGC-1α peroxisome proliferator-activated receptor gamma coactivator 1-alpha -- PI3K phosphatidylinositol 3′-kinase -- PMFs polymethoxyflavones -- PPAR γ peroxisome proliferator-activated receptor gamma -- PGE2 prostaglandin E2 -- PUMA p53 upregulated modulator of apoptosis -- RARD eamdom amplified polymorphis DNA -- RNS reactive nitrogen species -- ROS reactive oxygen species -- RUNX2 runt-related transcription factor 2 -- SIRT1 sirtuin 1 -- SQSTM1 sequestosome 1 -- SREBP1 sterol regulatory element-binding protein 1 -- TFAM transcription factor A, mitochondrial -- TGR5 Takeda G protein-coupled receptor 5 -- TNF-α tumor necrosis factor-alpha -- TRAP tartrate-resistant acid phosphatase -- UCP1 uncoupling protein 1 -- 6-BAP N6-benzyladenine -- β3AR beta-3 adrenoreceptor; Functional foods -- Analysis -- Periodicals; Food -- Biotechnology -- Periodicals; Nutrition -- Periodicals; 613.2
• DOI: 10.1016/j.jff.2022.105029
• Languages: English
• ISSNs: 1756-4646

Abstract

Graphical abstract: Highlights: The health benefits of Kaempferia spp. include antibacterial, anticancer, antidiabetic, cardiovascular protective, immunoregulatory, neuroprotective, and skin-whitening effects. Bioactive polymethoxyflavones and ethyl p-methoxycinnamate play a role in biological activity of Kaempferia spp.. Kaempferia spp. can target and regulate multiple pathways related to the enhancement of health and vitality. Studies related to value-added production of K. parviflora, such genotype × environment × management practices are limited. Abstract: Kaempferia spp. have traditionally played a role in treating various ailments and are attracting increasing economic and scientific interest. This review evaluates the traditional use, phytochemical compounds, and biological properties of Kaempferia parviflora, Kaempferia galanga, Kaempferia rotunda, Kaempferia pulchra, and Kaempferia angustifolia . The health benefits associated with consuming Kaempferia spp. and their active components, namely flavonoids and other volatile compounds, include antibacterial, anticancer, antidiabetic, cardiovascular protective, immunoregulatory, neuroprotective, and skin-whitening effects, suggesting the use of Kaempferia spp. as a potential health aid for the aging population. As agricultural production is important to ensure consistent quality of Kaempferia produce, resource management techniques related to species identification, cultivation, storage, and processing were also highlighted. It was suggested that the value-added concept in agricultural production may be limited. Investigations into plant biology and physiology are required to provide a solid theoretical basis for the sustainable production of Kaempferia .