Common Microbes and Antibiotic Resistance in Ocular Infections at an Urban Public Tertiary Care Hospital. (17th February 2022)

• Record Type: Journal Article
• Authors: Geevarghese, Alexi; Shah, Payal; Lopez, Jennifer; Tsui, Edmund; Raju, Leela
• Is Part Of: Ocular immunology and inflammation. Volume 30:Number 2(2022)
• Page Start: 481
• Page End: 486
• Publication Date: 2022-02-17
• Subjects: Microbial profile -- antibiotic resistance -- ocular infection -- conjunctivitis -- keratitis; Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.1080/09273948.2020.1799033
• Languages: English
• ISSNs: 0927-3948

Abstract

ABSTRACT: Purpose: We aim to describe ocular infection epidemiology for a public tertiary care hospital in New York City (NYC). Methods: We retrospectively reviewed 558 patients with ocular isolates from conjunctival, corneal, and intraocular culture from 2009 to 2017 for microbial growth and antimicrobial sensitivities. Results: In total, 185 ocular cultures (33%) had growth and the most commonly isolated microbes overall were Staphylococcus aureus (S. aureus) (23%), coagulase-negative Staphylococcus (CoNS) (23%), Pseudomonas aeruginos a (P. aeruginosa) (16%), and Streptococcus viridans (S. viridans) group (11%). The most common microbes within corneal (n = 61), conjunctival (n = 34), and intraocular isolates (n = 9) were P. aeruginosa (37.7%), S. aureus (35.3%), and S. viridans group (33.3%), respectively. Proportion of isolates exhibiting multi-drug resistance decreased over time ( P = .006). Conclusions: The microbial epidemiology of ocular infection of a public NYC hospital was distinct from other geographic locations, underscoring the importance of examining local profiles to more precisely inform empiric therapy.