Usage of image registration and three-dimensional visualization tools on serial computed tomography for the analysis of patients with traumatic intraparenchymal hemorrhages. (April 2022)

• Record Type: Journal Article
• Authors: Shih, Yun-Ju; Liu, Yan-Lin; Zhou, Jonathan T; Zhang, Yang; Chen, Jeon-Hor; Chen, Tai-Yuan; Yang, Cheng-Chun; Su, Min-Ying
• Is Part Of: Journal of clinical neuroscience. Volume 98(2022)
• Page Start: 154
• Page End: 161
• Publication Date: 2022-04
• Subjects: Imaging registration -- Three-dimensional -- Traumatic -- Intraparenchymal hemorrhage -- Contusion -- Computed tomography; Brain -- Surgery -- Periodicals; Neurosciences -- Periodicals; Nervous system -- Surgery -- Periodicals; Brain -- surgery -- Periodicals; Neurosurgical Procedures -- Periodicals; Neurosciences -- Periodicals; Electronic journals; 616.8
• DOI: 10.1016/j.jocn.2022.01.034
• Languages: English
• ISSNs: 0967-5868

Abstract

Highlights: Image registration and 3D videos help evaluation of traumatic IPH lesion evolution. Lesion centers between serial CT are closer (<1 cm) after registration. 3D videos show new lesions clearly (100%) among viewers. 3D videos are sensitive to demonstrate volume increase at one to two cc. Abstract: The aim of this study was to apply registration and three-dimensional (3D) display tools to assess the evolution of intraparenchymal hemorrhage (IPH) in patients with traumatic brain injury (TBI). We identified 109 TBI patients who had two computed tomography (CT) scans within 4 days retrospectively. The IPH was manually outlined. The registration was performed in 39 lesions from 29 patients with lesion volume < 1.5 cm on both baseline and follow-up CT. The center of mass (COM) of each lesion was calculated, and the distance between baseline and follow-up CT was used to evaluate the registration effect. The mean distances of COM before registration in the XYZ, XY, and YZ coordinates were 20.5 ± 10.2 mm, 17.8 ± 9.4 mm, and 15.9 ± 9.4 mm, respectively, which decreased significantly (p < 0.001) to 7.9 ± 4.9, 7.8 ± 5.0, and 6.1 ± 4.1 mm after registration. A 3D short video displaying the rendering view of all lesions in 34 randomly selected patients from baseline and follow-up scans were presented side-by-side for comparison. The detection rate of new IPH lesions increased in 3D videos (100%) as compared with axial CT slices (78.6–92.9%). A very high interrater agreement ( k = 0.856) on perceiving IPH lesion progression upon viewing 3D video was noted, and the absolute volume increase was significantly higher (p < 0.001) for progressive lesions (median 7.36 cc) over non-progressive lesions (median 0.01 cc). Compared to patients with spontaneous hemorrhagic stroke, evaluation of multiple small traumatic hemorrhages in TBI is more challenging. The applied image analysis and visualization methods may provide helpful tools for comparing changes between serial CT scans.