Malignant melanoma of the small bowel presenting with intussusception in a woman: a case report. (May 2017)

• Record Type: Journal Article
• Authors: Vrable, Abby; Chang, Richard
• Is Part Of: Melanoma management. Volume 4:Number 2(2017)
• Page Start: 99
• Page End: 104
• Publication Date: 2017-05
• Subjects: gastrointestinal melanoma -- HMB-45 -- interferon -- intussusception -- melanoma -- S100 -- small bowel; Melanoma -- Periodicals; 616.99477005
• DOI: 10.2217/mmt-2016-0028
• Languages: English
• ISSNs: 2045-0885

Abstract

Primary malignant melanoma originating in the small bowel is very rare. We report the case of primary malignant melanoma of the small bowel with secondary intussusception in a 51-year-old female with no prior history of cutaneous melanoma. The patient was admitted to the hospital for clinical bowel obstruction after 6 months of varying symptoms of antecedent syncopal events secondary to profound anemia due to iron deficiency followed later by vomiting, abdominal pain and weight loss. A CT scan showed intussusception and she underwent a small bowel resection. Diagnosis of malignant melanoma was confirmed post-operatively following immunohistochemistry. The patient history and postoperative investigation excluded the existence of a primary lesion elsewhere. Our case represents an aggressive primary small bowel melanoma presenting as intussusception.