Constructing Benchmark Databases and Protocols for Medical Image Analysis: Diabetic Retinopathy. (19th June 2013)

• Record Type: Journal Article
• Authors: Kauppi, Tomi; Kämäräinen, Joni-Kristian; Lensu, Lasse; Kalesnykiene, Valentina; Sorri, Iiris; Uusitalo, Hannu; Kälviäinen, Heikki
• Other Names: Cattani Carlo Academic Editor.
• Is Part Of: Computational and mathematical methods in medicine. Volume 2013(2013)
• Publication Date: 2013-06-19
• Subjects: Medicine -- Computer simulation -- Periodicals; Medicine -- Mathematical models -- Periodicals; 610.11
• DOI: 10.1155/2013/368514
• Languages: English
• ISSNs: 1748-670X

Abstract

Abstract : We address the performance evaluation practices for developing medical image analysis methods, in particular, how to establish and share databases of medical images with verified ground truth and solid evaluation protocols. Such databases support the development of better algorithms, execution of profound method comparisons, and, consequently, technology transfer from research laboratories to clinical practice. For this purpose, we propose a framework consisting of reusable methods and tools for the laborious task of constructing a benchmark database. We provide a software tool for medical image annotation helping to collect class label, spatial span, and expert's confidence on lesions and a method to appropriately combine the manual segmentations from multiple experts. The tool and all necessary functionality for method evaluation are provided as public software packages. As a case study, we utilized the framework and tools to establish the DiaRetDB1 V2.1 database for benchmarking diabetic retinopathy detection algorithms. The database contains a set of retinal images, ground truth based on information from multiple experts, and a baseline algorithm for the detection of retinopathy lesions.