Phages and immunomodulation. (August 2017)

• Record Type: Journal Article
• Authors: Górski, Andrzej; Dąbrowska, Krystyna; Międzybrodzki, Ryszard; Weber-Dąbrowska, Beata; Łusiak-Szelachowska, Marzanna; Jończyk-Matysiak, Ewa; Borysowski, Jan
• Is Part Of: Future microbiology. Volume 12:Number 10(2017)
• Page Start: 905
• Page End: 914
• Publication Date: 2017-08
• Subjects: cytokines -- gut -- immunity -- lymphocytes -- microbiome -- phages -- platelets; Microbiology -- Research -- Periodicals; 616.9041
• DOI: 10.2217/fmb-2017-0049
• Languages: English
• ISSNs: 1746-0913

Abstract

In the past years, the microbiome and its role in the pathophysiology of diseases have gained great interest. The progress of our knowledge in this field opens completely novel prospects for treating disorders, including those which are most challenging to medicine today. Of special interest are studies on the interactions of the microbiome with the immune system. Only recently has the presence of bacteriophages in the microbiome been highlighted, and their potential role in maintaining normal immunity has gained increasing attention. We summarize the available data pointing to the potential impact of phages in maintaining immunological homeostasis.