Dichlormethan, Addendum [BAT Value Documentation in German language, 2016]. Issue 4 (26th October 2016)

• Record Type: Journal Article
• Authors: Bolt, H. M.; Weistenhöfer, W.; Drexler, H.; Hartwig, A.
• Is Part Of: MAK collection for occupational health and safety. Volume 1:Issue 4(2016)
• Page Start: 2677
• Page End: 2680
• Publication Date: 2016-10-26
• Subjects: Dichlormethan -- Methylenchlorid -- Methylendichlorid -- Methylenbichlorid -- Methylenum chloratum -- Arbeitsstoff -- biologischer Toleranzwert -- BAT‐Wert -- EKA -- Toxizität; Biological monitoring -- Periodicals; Industrial toxicology -- Periodicals; Hazardous substances -- Periodicals; 615.902
• DOI: 10.1002/3527600418.bb7509d0022
• Languages: English
• ISSNs: 2509-2383

Abstract

Addendum to Dichloromethane: The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re‐evaluated dichloromethane, considering dichloromethane in blood to characterize the internal exposure. In a chamber study, 14 non‐smokers were exposed to different concentrations of dichloromethane. After exposure to the present MAK‐value of 50 ml dichloromethane/m 3 without physical activity, a concentration of 0.3 mg dichloromethane/l blood was measured. Considering an increased intake due to elevated breathing volume during work, the exposure to 50 ml dichloromethane/m 3 results in a blood concentration of 0.5 mg/l. Taking into account this study and the EKA correlation of 2001, a BAT‐value of 500 µg dichloromethane/l blood was evaluated. Sampling time is straight after exposure.