Human Papillomavirus and Oral Lesions: What is the Best Diagnostic Method?. Issue 3 (15th May 2022)

• Record Type: Journal Article
• Authors: Fiorillo, Luca; Cervino, Gabriele; Surace, Giovanni; Fiorillo, Maria Teresa; Meto, Agron; Cicciu, Marco
• Is Part Of: Journal of craniofacial surgery. Volume 33:Issue 3(2022)
• Page Start: e279
• Page End: e281
• Publication Date: 2022-05-15
• Subjects: Dentistry -- diagnostic errors -- histological techniques -- human papillomavirus -- polymerase chain reaction -- precancerous conditions; Facial bones -- Surgery -- Periodicals; Skull -- Surgery -- Periodicals; Face -- Surgery -- Periodicals; Surgery, Plastic -- Periodicals; 617.52
• DOI: 10.1097/SCS.0000000000008113
• Languages: English
• ISSNs: 1049-2275

Abstract

Abstract : Abstract: Oropharyngeal squamous cell carcinoma is the most common neoplasm of head and neck cancers related to the presence of human papillomavirus (HPV). in the dental, maxillofacial and ENT fields, the finding of mediated HPV lesions is quite common. The diagnostic techniques currently available are different and can be more or less invasive depending on the type of lesion and the need for the clinician. In this study, two clinical cases subjected to a double diagnostic technique were considered in order to exclude any possible risk of false negatives. The polymerase chain reaction (PCR) technique showed a lower sensitivity or in any case dictated by a limited number of HPV strains analyzed. Histological examination nowadays turns out to be the best diagnostic method despite requiring a surgical phase.