Cardiac metastasis causes paradoxical malignant embolism. Issue 5 (15th July 2021)

• Record Type: Journal Article
• Authors: Wagner, Britta Janina; Hobbach, Hans‐Peter; Hobbach, Anastasia Janina; Hieggelke, Lena Katharina; Grond, Martin; Monsefi, Nadejda; Buettner, Reinhard
• Is Part Of: Cancer reports. Volume 5:Issue 5(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-07-15
• Subjects: cardiac metastasis -- malignant embolism -- paradox embolism -- pulmonal adenocarcinoma; Cancer -- Periodicals; 616.994005
• DOI: 10.1002/cnr2.1513
• Languages: English
• ISSNs: 2573-8348

Abstract

Abstract: Background: Embolic events play an important role in clinical everyday practice. Malignant arterial embolism is a rare nevertheless often fatal entity for cardiac, cerebral or systemic ischemia, requiring immediate diagnosis and treatment. Case: This is a case report of a 65 years‐old female, suffering from pulmonal adenocarcinoma, who was hospitalized due to neurological deficits caused by an acute ischemic stroke, followed by anterior myocardial infarction within 3 days. Diagnostic work‐up revealed metastasis of the pulmonal adenocarcinoma in the right atrium and a patent foramen ovale. Histopathological examination of the coronary embolus verified paradoxical arterial embolism of the pulmonal adenocarcinoma into a coronary vessel and consequently cerebral arteries. Conclusion: The present case underlines the need for (i), consideration of malignant embolism, (ii) histopathological examination of the embolus to determine its etiology, and (iii) interdisciplinary discussion of individual therapeutic and prevention strategies in cancer patients with cerebral, cardiac or systemic embolic events.