Metastatic rectal cancer in the ampulla of Vater: A unique case. Issue 5 (17th July 2021)

• Record Type: Journal Article
• Authors: Samara, Athina A.; Sgantzou, Ioanna‐Konstantina; Diamantis, Alexandros; Kokkalis, Alexandros; Tsapakidis, Konstantinos; Tolia, Maria; Christodoulidis, Gregory; Rountas, Christos; Zacharoulis, Dimitris
• Is Part Of: Cancer reports. Volume 5:Issue 5(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-07-17
• Subjects: immunochemistry -- metastatic -- rectal cancer -- secondary -- Vater; Cancer -- Periodicals; 616.994005
• DOI: 10.1002/cnr2.1510
• Languages: English
• ISSNs: 2573-8348

Abstract

Abstract: Background: A metastatic lesion located in the ampulla of Vater is considered extremely rare, with only 32 cases reported globally. Case: A 65‐year‐old patient was primarily diagnosed with a rectal adenocarcinoma. Twenty‐four months later as part of the oncological follow‐up, the patient was diagnosed with a single secondary tumor in the ampulla of Vater. After undergoing a pancreaticoduodenectomy (Whipple procedure), the patient experienced an uneventful recovery and received adjuvant chemotherapy. Sixteen months later the patient remained disease‐free. Conclusion: To the best of our knowledge, the present case represents the first reported metastatic tumor in the ampulla of Vater, originating from a rectal adenocarcinoma. This case underlines the critical role of immunohistochemistry in arriving at a correct diagnosis in order to guide clinical decision‐making.