Incidence of urinary tract infection following initiation of intermittent catheterization among patients with recent spinal cord injury in Germany and the Netherlands. (4th May 2022)

• Record Type: Journal Article
• Authors: Berger, Ariel; Goldstine, Jimena; Hofstad, Cheriel; Inglese, Gary W.; Kirschner-Hermanns, Ruth; MacLachlan, Sharon; Shah, Surbhi; Vos-van der Hulst, Marije; Weiss, Jerome
• Is Part Of: Journal of spinal cord medicine. Volume 45:Number 3(2022)
• Page Start: 461
• Page End: 471
• Publication Date: 2022-05-04
• Subjects: Urinary tract infection -- Chart review -- Intermittent catheterization -- Spinal cord injury -- Antibiotics; Spinal cord -- Wounds and injuries -- Periodicals; Spinal cord -- Diseases -- Periodicals; 616.8305
• DOI: 10.1080/10790268.2020.1829416
• Languages: English
• ISSNs: 1079-0268

Abstract

Abstract : Objective: To assess incidence of urinary tract infection (UTI) among patients with recent spinal cord injury (SCI) who initiated intermittent catheterization (IC). Design: Retrospective chart review. Setting: Two European SCI rehabilitation centers. Participants: Seventy-three consecutive patients with recent SCI who initiated IC. Outcome measures: Incidence of UTI, using six different definitions, each based on microbiology ± symptomatology ± mention of UTI . Rates were expressed in terms of numbers of UTIs per 100 patient-months (PMs). Attention was focused on first-noted UTI during the three-month follow-up, as assessed with each of the six definitions. Results: Fifty-eight percent of patients ( n = 33) met ≥1 definitions for UTI during follow-up (rate: 31.5 UTIs per 100 PMs), ranging from 14% (5.3 per 100 PMs; definition requiring bacteriuria, pyuria, and presence of symptoms) to 45% (22.7 per 100 PMs; definition requiring "mention of UTI"). Ten cases were identified using the definition that required bacteriuria, pyuria, and symptoms, whereas definitions that required bacteriuria and either pyuria or symptoms resulted in the identification of 20–25 cases. Median time to UTI ranged from 42 days ("mention of UTI") to 81 days (definition requiring bacteriuria and ≥100 leukocytes/mm 3 ). Conclusion: Depending on definition, 14% to 45% of patients with recent SCI experience UTI within three months of initiating IC. Definitions requiring bacteriuria and either pyuria or symptoms consistently identified about twice as many cases as those that required all three conditions. Standardizing definitions may help improve detection, treatment, and prevention of UTI within this vulnerable population.