Green Approach of Solvent- and Catalyst Free Synthesis of Bis(indolyl)methanes under Visible Light Irradiation. (21st April 2022)

• Record Type: Journal Article
• Authors: Hote, Baliram S.; Siddiqui, Tabbasum A. J.; Pisal, Parshuram M.; Mandawad, Gajanan G.
• Is Part Of: Polycyclic aromatic compounds. Volume 42:Number 4(2022)
• Page Start: 1761
• Page End: 1769
• Publication Date: 2022-04-21
• Subjects: Bis(indolyl)methanes -- indole -- visible light; Polycyclic aromatic compounds -- Periodicals; 547
• DOI: 10.1080/10406638.2020.1804414
• Languages: English
• ISSNs: 1040-6638

Abstract

Abstract: An efficient procedure has been developed for the synthesis of bis(indolyl)methanes (3a-m) from condensation of indole (1) and various substituted aromatic aldehydes (2a-m) is described. The aromatic electrophilic substitution reactions of indole (1) with and various substituted aromatic aldehydes (2a-m) are achieved in solvent- and catalyst free condition using irradiation with 150W tungsten lamp (visible light irradiation). This methodology offers several advantages such as good yields, simple procedure, mild and environmentally benign conditions.