Outcomes of sacrocolpopexy/sacrohysteropexy with mesh placement targeted to affected compartment. (May 2022)

• Record Type: Journal Article
• Authors: Rusavy, Zdenek; Najib, Bernard; Abdelkhalek, Yara; Grinstein, Ehud; Gluck, Ohad; Deval, Bruno
• Is Part Of: European journal of obstetrics, gynecology, and reproductive biology. Volume 272(2022)
• Page Start: 188
• Page End: 192
• Publication Date: 2022-05
• Subjects: Laparoscopic sacrocolpopexy -- Sacrohysteropexy -- Pelvic organ prolapse -- Mesh -- Single compartment; POP Pelvic organ prolapse -- QoL Quality of life -- SUI Stress urinary incontinence -- AI Anal incontinence; Obstetrics -- Periodicals; Gynecology -- Periodicals; Reproductive health -- Periodicals; Gynecology -- Periodicals; Obstetrics -- Periodicals; Reproduction -- Periodicals; Obstétrique -- Périodiques; Gynécologie -- Périodiques; Reproduction -- Périodiques; Verloskunde; Gynaecologie; Voortplanting (biologie); Gynecology; Obstetrics; Reproduction; Electronic journals; Periodicals; Electronic journals; 618.05
• DOI: 10.1016/j.ejogrb.2022.03.037
• Languages: English
• ISSNs: 0301-2115

Abstract

Highlights: Implantation of a single sheet of mesh was not associated with inferior outcome to implantation of mesh to both compartments. Laparoscopic sacrocolpopexy with a single sheet of mesh placed into the affected compartment along with apical suspension does not provoke a de novo prolapse in the other compartment. Single sheet laparoscopic sacrocolpopexy or sacrohysteropexy is a safe and effective option to reduce the amount of implanted synthetic mesh. Abstract: Objective: No recommendation regarding the number of meshes to be implanted in laparoscopic genital prolapse surgery exists. Is it necessary to implant a mesh into a compartment that is not affected to prevent its prolapse in the follow-up? Our objective was to compare the long-term outcomes of laparoscopic sacrocolpopexy according to compartments where mesh was implanted. Study design: This is a retrospective cohort study of 328 patients after laparoscopic sacrocolpopexy at our centre in 7/2005 – 3/2021. 294 patients with perioperative data and POP-Q and/or prolapse symptoms in mean follow-up of 42.8 months was available for the outcome analysis. Surgical failure was defined as prolapse beyond hymen, subjective recurrence or retreatment. The women were divided into four groups depending on compartments, where the mesh was implanted. Group A – anterior, group P – posterior, Group AP – compound of patients with anterior or posterior single arm mesh placement and (B), with anterior and posterior arm placement. Groups AP and B were compared for feasibility of single compartment mesh implantation. Comparison of groups A and P allowed assessment of non-inferiority of single anterior vs. posterior compartment placement. The data were compared using Wilcoxon Two Sample test, Chi-square test or Fisheŕs Exact test, p-value < 0.05 was considered statistically significant. Results: A single compartment mesh implantation was associated with shorter operating time and hospital stay and comparable incidence of complications. A statistically significant difference in all POP-Q points in favour of group B was observed, however, with comparable rate of prolapse beyond hymen(6.3%AP vs. 7.8%B). Similar frequency of surgical failure (17.5%AP vs. 13.8%B) and incidence of de novo pelvic floor disorders or pain was observed. Comparison of groups A and P showed higher suspension of point C in group P(−2.6 vs. −4.0, p < 0.05) with no difference in points Ba, Bp, surgical failure rate and de novo pelvic floor disorders. Conclusion: Implantation of a single sheet of mesh was not associated with inferior outcome to implantation of mesh to both compartments. Laparoscopic sacrocolpopexy with a single mesh arm placed into the affected compartment along with apical suspension does not induce a de novo prolapse in unoperated compartment.