Recovery of dialysis patients with COVID-19: health outcomes 3 months after diagnosis in ERACODA. Issue 6 (14th January 2022)

• Record Type: Journal Article
• Authors: Hemmelder, Marc H; Noordzij, Marlies; Vart, Priya; Hilbrands, Luuk B; Jager, Kitty J; Abrahams, Alferso C; Arroyo, David; Battaglia, Yuri; Ekart, Robert; Mallamaci, Francesca; Malloney, Sharon-Rose; Oliveira, Joao; Rydzewski, Andrzej; Sridharan, Sivakumar; Vogt, Liffert; Duivenvoorden, Raphaël; Gansevoort, Ron T; Franssen, Casper F M
• Is Part Of: Nephrology dialysis transplantation. Volume 37:Issue 6(2022)
• Page Start: 1140
• Page End: 1151
• Publication Date: 2022-01-14
• Subjects: COVID-19 -- dialysis -- functional health status -- mental health status -- survival; Nephrology -- Periodicals; Hemodialysis -- Periodicals; Kidneys -- Transplantation -- Periodicals; Hemodialysis; Kidneys -- Transplantation; Nephrology; Periodicals; 616.61
• DOI: 10.1093/ndt/gfac008
• Languages: English
• ISSNs: 0931-0509

Abstract

ABSTRACT: Background: Coronavirus disease 2019 (COVID-19)-related short-term mortality is high in dialysis patients, but longer-term outcomes are largely unknown. We therefore assessed patient recovery in a large cohort of dialysis patients 3 months after their COVID-19 diagnosis. Methods: We analyzed data on dialysis patients diagnosed with COVID-19 from 1 February 2020 to 31 March 2021 from the European Renal Association COVID-19 Database (ERACODA). The outcomes studied were patient survival, residence and functional and mental health status (estimated by their treating physician) 3 months after COVID-19 diagnosis. Complete follow-up data were available for 854 surviving patients. Patient characteristics associated with recovery were analyzed using logistic regression. Results: In 2449 hemodialysis patients (mean ± SD age 67.5 ± 14.4 years, 62% male), survival probabilities at 3 months after COVID-19 diagnosis were 90% for nonhospitalized patients ( n = 1087), 73% for patients admitted to the hospital but not to an intensive care unit (ICU) ( n = 1165) and 40% for those admitted to an ICU ( n = 197). Patient survival hardly decreased between 28 days and 3 months after COVID-19 diagnosis. At 3 months, 87% functioned at their pre-existent functional and 94% at their pre-existent mental level. Only few of the surviving patients were still admitted to the hospital (0.8–6.3%) or a nursing home (∼5%). A higher age and frailty score at presentation and ICU admission were associated with worse functional outcome. Conclusions: Mortality between 28 days and 3 months after COVID-19 diagnosis was low and the majority of patients who survived COVID-19 recovered to their pre-existent functional and mental health level at 3 months after diagnosis.