A review on antiviral efficacy of Bifidobacterium species. Issue 2 (27th April 2022)

• Record Type: Journal Article
• Authors: Abdi, Milad; Ranjbar, Reza
• Is Part Of: Reviews and research in medical microbiology. Volume 33:Issue 2(2022)
• Page Start: 74
• Page End: 81
• Publication Date: 2022-04-27
• Subjects: antiviral effect -- bifidobacterium -- probiotic; Medical microbiology; Periodicals; 616.9041
• DOI: 10.1097/MRM.0000000000000295
• Languages: English
• ISSNs: 2770-3150

Abstract

Abstract : Viral infections like diarrheal infections (Rotavirus diarrhea) and respiratory infections transmitted virus (influenza virus [IFV]) are of the most common diseases in humans. Studies have shown that probiotics are able to decrease the risk or duration of viral infection symptoms. The purpose of this paper is to review the current studies on the efficacy of Bifidobacterium spp on viral infections and to provide insights on their possible antiviral mechanisms. A PubMed, Scopus, and Google Scholar database search was performed up to February 2021 using appropriate search terms The terms 'probiotic', 'bifidobacterium' and 'virus'. Altogether, 21 relevant studies were obtained which 8, 4, and 9 studies were related to antiviral efficacy of Bifidobacterium spp on Rotavirus, IFV, and other viruses, respectively. Based on reviewed studies, Bifidobacterium spp may exert their antiviral effects via direct interaction or via stimulation of the immune system. More in vitro, in vivo, and clinical trials are needed to evaluate the antiviral efficacy and mechanisms of Bifidobacterium spp.