Pancreatic leiomyosarcoma in a domestic shorthair cat. Issue 1 (June 2022)

• Record Type: Journal Article
• Authors: Bobis Villagrá, Diego; Almeida, Mariana; Cox, Alistair; Henderson, Elisabeth
• Is Part Of: Journal of feline medicine and surgery open reports. Volume 8:Issue 1(2022)
• Publication Date: 2022-06
• Subjects: Leiomyosarcoma -- pancreatic neoplasia -- mesenchymal tumour -- immunohistochemistry -- oncology surgery; Cats -- Diseases -- Periodicals; Cats -- Surgery -- Periodicals; 636.8089
• DOI: 10.1177/20551169221098328
• Languages: English
• ISSNs: 2055-1169

Abstract

Case summary: A 7-year-old female neutered domestic shorthair cat was presented with weight loss, abdominal distension, lethargy, pyrexia and hyporexia. Haematology and biochemistry were unremarkable. Abdominal ultrasound revealed a cystic mass within the left cranial abdominal quadrant, adjacent to the pancreas, stomach and spleen. CT revealed a 10.5 cm, rounded, well-encapsulated, hypodense mass arising from the left pancreatic lobe. The remaining organs of the abdominal and thoracic cavity were unremarkable. A partial left lobe pancreatectomy and splenic lymph node removal were performed. Histopathology of the pancreatic mass reported a proliferating population of neoplastic spindle cells most consistent with a preliminary diagnosis of soft tissue sarcoma. Immunohistochemistry characteristics, together with the morphological findings, were consistent with a diagnosis of leiomyosarcoma. The patient recovered without any concerns after receiving routine postoperative care. Clinical examination and abdominal ultrasound 5 months postoperatively revealed no abnormalities. Relevance and novel information: To our knowledge, this is the first report of pancreatic leiomyosarcoma in a cat. Pancreatic leiomyosarcoma should be considered as one of the possible differential diagnoses for cats presenting with a pancreatic mass.