Viable SARS-CoV-2 shedding under remdesivir and dexamethasone treatment. Issue 6 (June 2022)

• Record Type: Journal Article
• Authors: Yoon, Jin Gu; Yoo, Jin Sae; Lee, Jungmin; Hyun, Hak-Jun; Seong, Hye; Noh, Ji Yun; Cheong, Hee Jin; Kim, Woo Joo; Kim, Young Rong; Heo, Jung Yeon; Bae, Joon-Yong; Cui, Chunguang; Lee, Sohyun; Park, Man-Seong; Song, Joon Young
• Is Part Of: Journal of infection. Volume 84:Issue 6(2022)
• Page Start: 834
• Page End: 872
• Publication Date: 2022-06
• Subjects: Infection -- Periodicals; Bacterial Infections -- Periodicals; Communicable Diseases -- Periodicals; Electronic journals; 616.905
• DOI: 10.1016/j.jinf.2022.03.022
• Languages: English
• ISSNs: 0163-4453

Abstract

Highlights: The cycle threshold (Ct) value of RT-PCR was not significantly reduced by remdesivir. Infectious virus was not detected after the third dose of remdesivir despite dexamethasone treatment. SARS-CoV-2 shedding significantly decreased after remdesivir treatment, regardless of the Ct value. Rapid antigen test is a viable adjunctive tool that guides the decision to terminate the isolation.