Lantana camara Linn root extract-mediated gold nanoparticles and their in vitro antioxidant and cytotoxic potentials. (19th May 2017)

• Record Type: Journal Article
• Authors: Ramkumar, Rajendiran; Balasubramani, Govindasamy; Raja, Ramalingam Karthik; Raja, Manickam; Govindan, Raji; Girija, Easwaradas Kreedapathy; Perumal, Pachiappan
• Is Part Of: Artificial cells, nanomedicine, and biotechnology. Volume 45:Number 4(2017)
• Page Start: 748
• Page End: 757
• Publication Date: 2017-05-19
• Subjects: Lantana camara -- Au NPs -- HR-TEM -- DPPH -- MDA-MB-231; Artificial cells -- Periodicals; Nanotechnology -- Periodicals; Blood substitutes -- Periodicals; Tissue engineering -- Periodicals; Molecules -- Periodicals; Biotechnology -- Periodicals; 615.39
• DOI: 10.1080/21691401.2016.1276923
• Languages: English
• ISSNs: 2169-1401

Abstract

Abstract: The Lantana camara Linn root extract derived gold nanoparticles (Au NPs) were characterized by Ultraviolet-Visible spectroscopy, X-ray diffraction, fourier transform-infrared, high resolution transmission electron microscopy, selected area electron diffraction pattern and energy dispersive X-ray analyses. In DPPH assay, the inhibitory concentration (IC50 ) of Au NPs and gallic acid was 24.17 and 5.39 μg/ml, whereas, for cytotoxicity assay, the IC50 of Au NPs was 17.72 and 32.98 μg/ml on MBA-MB-231 and Vero cells, respectively. Thus, the Au NPs possess significant in vitro antioxidant and cytotoxic properties which could be considered as potential alternate for the development of anticancer drug in future.