Efficacy of Intragastric Balloon Placement and Botulinum Toxin Injection in Bariatric Endoscopy. Issue 6 (December 2020)

• Record Type: Journal Article
• Authors: Kanlioz, Murat; Ekici, Uğur; Tatli, Faik; Karatas, Turgay
• Is Part Of: Surgical laparoscopy endoscopy & percutaneous techniques. Volume 30:Issue 6(2020)
• Publication Date: 2020-12
• Subjects: gastric balloon -- gastric botulinum toxin -- obesity and obesity treatment -- bariatric endoscopy -- body mass index; Endoscopic surgery -- Periodicals; Laparoscopic surgery -- Periodicals; Endoscopy -- Periodicals; Laparoscopy -- Periodicals; 617.550597
• DOI: 10.1097/SLE.0000000000000829
• Languages: English
• ISSNs: 1530-4515

Abstract

Abstract : Background: To evaluate the results obtained from the combination of intragastric botulinum toxin A (IGBTA), intragastric balloon (IGB), and IGBTA(+)IGB in the treatment of obesity. Materials and Methods: Three separate treatment groups were set up. IGBTA, IGB, and IGBTA(+)IGB were administered to Group 1, 2, and 3, respectively. The body mass indexes (BMI) of patients were measured before and 6 months after the treatment. The intragroup and intergroup treatment results have been evaluated. P <0.05 was considered significant. Results: The mean BMI decreased by 1.6 kg/m 2 in 40 patients who received IGBTA in group 1 ( P <0.001), 3.95 kg/m 2 in 42 patients who received IGB in group 2 ( P <0.001), and 4.9 kg/m 2 in 39 patients who received IGBTA and IGB in group 3 ( P <0.001) after 6 months of treatment. The intolerance because of the application was the highest in group 3, followed by group 2. Conclusion: The treatment was most successful in group 3 followed by group 2 and group 1, respectively. The authors recommend the group 3 treatment, provided that nausea, vomiting, and flatulence have a high index of probability in such a treatment. However, when deciding between group 1 and group 2 treatments, the authors recommend opting for group 2 treatment that shows to be more efficient.