Validation and Cardiorespiratory Response of the 1-Min Sit-to-Stand Test in Interstitial Lung Disease. Issue 12 (December 2020)

• Record Type: Journal Article
• Authors: TREMBLAY LABRECQUE, PIERRE-FRANÇOIS; HARVEY, Jany; NADREAU, ÉRIC; MALTAIS, FRANÇOIS; DION, GENEVIÈVE; SAEY, DIDIER
• Is Part Of: Medicine and science in sports and exercise. Volume 52:Issue 12(2020)
• Publication Date: 2020-12
• Subjects: LUNG DISEASES, INTERSTITIAL -- EXERCISE TEST -- WALK TEST -- PHYSICAL AND REHABILITATION MEDICINE; Sports medicine -- Periodicals; Exercise -- Physiological aspects -- Periodicals; Exercise -- Health aspects -- Periodicals; 612.044
• DOI: 10.1249/MSS.0000000000002423
• Languages: English
• ISSNs: 0195-9131

Abstract

ABSTRACT: Purpose: To assess the 1-min sit-to-stand test (1STS) test–retest reliability and construct validity and its associated cardiorespiratory response in comparison to the 6-min walk test (6MWT) and symptom-limited cycling cardiopulmonary exercise test (CPET) in people with interstitial lung disease (ILD). Methods: Fifteen participants with ILD performed two 1STS tests, a 6MWT and a CPET. The three tests were administered on three separate visits, and cardiorespiratory parameters were continuously recorded during the tests. Results: The number of repetitions during both 1STS tests was 22 ± 4 and 22 ± 4 (mean difference of 0.53 ± 2.00 repetitions, P = 0.32) with an intraclass correlation of 0.937 (95% confidence interval, 0.811–0.979]) and a minimal detectable change of 2.9 repetitions. The number of 1STS repetitions was highly correlated with the 6MWT distance ( r = 0.823, P < 0.001) and with the peak cycling power output expressed in % predicted values ( r = 0.706, P < 0.003). Oxygen consumption (V˙O2 ) peak during the 1STS reached 83% and 78% of V˙O2 peak during 6MWT and CPET, respectively. Peak 1STS HR, minute ventilation ( V ˙E, ), V˙O2 values, as well as nadir SpO2 were achieved during the recovery phase of the test, whereas peak 6MWT and CPET HR, V ˙E, V˙O2 and nadir SpO2 always occurred at the end of the test. The three tests elicited a similar fall in SpO2 ranging between 8% and 12%. Symptom scores after the 1STS were similar to those seen at the end of the 6MWT but lower than those of CPET. Conclusions: The 1STS showed excellent test–retest reliability in patients with ILD in whom it elicited a substantial, but submaximal cardiorespiratory response. Our data also support the construct validity of the 1STS to assess functional exercise capacity in patients with ILD and to detect exercise-induced O2 desaturation. Abstract : Supplemental digital content is available in the text.