Maternal, Perinatal and Neonatal Outcomes With COVID-19: A Multicenter Study of 242 Pregnancies and Their 248 Infant Newborns During Their First Month of Life. Issue 12 (December 2020)

• Record Type: Journal Article
• Authors: Marín Gabriel, Miguel A; Reyne Vergeli, Mar; Caserío Carbonero, Sonia; Sole, Laia; Carrizosa Molina, Tamara; Rivero Calle, Irene; Cuadrado Pérez, Irene; Álvarez Fernández, Blanca; Forti Buratti, Azul; Fernández-Cañadas Morillo, Aurora
• Is Part Of: Pediatric infectious disease journal. Volume 39:Issue 12(2020)
• Publication Date: 2020-12
• Subjects: COVID19 -- newborn -- SARS coronavirus 2 -- breast-feeding -- cesarean delivery; Communicable diseases in children -- Periodicals; Infection in children -- Periodicals; 618.929
• DOI: 10.1097/INF.0000000000002902
• Languages: English
• ISSNs: 0891-3668

Abstract

Abstract : Background: Our aim was to describe the clinical features of mothers with coronavirus disease 2019 (COVID-19) infection during gestation or delivery, and the potential vertical transmission. We also wish to evaluate the possible horizontal transmission after hospital discharge, by means of a follow-up of all the newborns included at 1 month of age. Methods: This multicenter descriptive study involved 16 Spanish hospitals. We reviewed the medical records of 242 pregnant women diagnosed with COVID-19 from March 13 to May 31, 2020, when they were in their third trimester of pregnancy. They and their 248 newborn infants were monitored until the infant was 1 month old. Results: Caesarean sections (C-sections) were performed on 63 (26%) women. The initial clinical symptoms were coughing (33%) and fever (29.7%). Mothers hospitalized due to COVID-19 pathology had a higher risk of ending their pregnancy via C-section ( P = 0.027). Newborns whose mothers had been admitted due to their COVID-19 infection had a higher risk of premature delivery ( P = 0.006 ). We admitted 115 (46.3%) newborn infants to the neonatal unit, of those, 87 (75.6%) were only admitted due to organizational circumstances. No infants died and no vertical or horizontal transmission was detected. Regarding type of feeding, 41.7% of the newborns received exclusive breast-feeding at discharge and 40.4% at 1 month. Conclusions: We did not detect COVID-19 transmission during delivery or throughout the first month of life in the newborns included in our study. Exclusive breast-feeding rates at discharge and at 1 month of age were lower than expected.