Palladium-catalyzed regioselective hydrosulfonylation of allenes with sulfinic acids. Issue 14 (18th March 2022)

• Record Type: Journal Article
• Authors: Li, Luan-Ying; Leng, Bo-Rong; Li, Jia-Zhuo; Liu, Qing-Quan; Yu, Jianguang; Wei, Ping; Wang, De-Cai; Zhu, Yi-Long
• Is Part Of: RSC advances. Volume 12:Issue 14(2022)
• Page Start: 8443
• Page End: 8448
• Publication Date: 2022-03-18
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/d1ra09036d
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : A simple palladium-based catalytic system for hydrosulfonylation of allenamides was established. Various nitrogen-containing linear allylic sulfones can be generated in moderate to excellent yield with E -selectivity and 100% atom utilization. Abstract : An atom-economic method of preparing allylic sulfones via hydrosulfonylation of allenes with sulfinic acids under Pd(0)-catalysis was reported. This process has a high degree of regio- and stereoselectivity, and provides the target product with a moderate to excellent yield. A wide range of nitrogen- or oxygen-containing linear E -allylic sulfones have been synthesized. With the support of experimental research, a possible mechanism was proposed.