Synthesis of a Near‐Infrared Fluorescence Turn‐On Probe Based on Dicyanoisophorone for HS−‐Detection in Cancer Cells and Zebrafish in Pure Water Media. Issue 17 (3rd May 2022)

• Record Type: Journal Article
• Authors: Huang, Xuelong; Lan, Ning; Jiang, Fan; He, Haifeng; Zhong, Jiang
• Is Part Of: ChemistrySelect. Volume 7:Issue 17(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-05-03
• Subjects: near-infrared -- HS− anions -- dicyanoisophorone -- HeLa cells -- zebrafish -- water; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/slct.202201070
• Languages: English
• ISSNs: 2365-6549

Abstract

Abstract: It is still a huge challenge to develop novel near‐infrared (NIR) probes with high selectivity and sensitivity for the detection of HS − anions in pure water medium. Herein, a novel dicyanoisophorone‐based NIR fluorescent turn‐on probe for HS − anions is reported. This probe displays a highly selective and sensitive (detection limit: 1.35 μM) with emission wavelength at 675 nm in pure water by using a schiff base group as a selective reaction site for HS − . Moreover, probe DCI‐SB can be used for tracking HS − anions in HeLa cells and zebrafish, indicating that it can be potentially applied for HS − anions sensing in biology fields. Abstract : Insert text for Table of Contents here.A novel dicyanoisophorone‐based near‐infrared fluorescent turn‐on probe DCI‐SB for HS − anions is reported. This probe displays a highly selective and sensitive (detection limit: 1.35 μM) with emission wavelength at 675 nm in pure water by using a schiff base group as a selective reaction site for HS − . Moreover, probe DCI‐SB can be used for tracking HS − anions in HeLa cells and zebrafish, indicating that it can be potentially applied for HS − anions sensing in biology fields.