Orbital and periorbital dermoid cysts: a retrospective analysis of 270 lesions. (4th May 2022)

• Record Type: Journal Article
• Authors: Kim, Diana H.; Prat, Daphna Landau; Tadros, Samuel; Katowitz, William R.
• Is Part Of: Orbit. Volume 41:Number 3(2022)
• Page Start: 341
• Page End: 345
• Publication Date: 2022-05-04
• Subjects: Childhood tumor -- choristoma -- dermoid cyst -- periorbital tumor; Eye-sockets -- Surgery -- Periodicals; Eye-sockets -- Diseases -- Periodicals; Orbit -- surgery -- Periodicals; Orbital Diseases -- Periodicals; 617.7
• DOI: 10.1080/01676830.2021.1912114
• Languages: English
• ISSNs: 0167-6830

Abstract

ABSTRACT: Purpose: To report the clinical characteristics and intraoperative findings of periorbital and orbital dermoid cysts and their relationship to location and rupture. Methods: Retrospective review of 270 cases with orbital or periorbital dermoid cysts that presented over a period of 11 years. Patients were included if diagnosis of dermoid cyst was made by histopathologic analysis. Clinical characteristics and operative outcomes were recorded and analyzed with Chi-squared analyses or univariate regression. Multivariate binary logistic regression was performed to assess predictors of location and rupture. Results: Dermoids frequently occurred unilaterally and were more frequently described as mobile (61.5%), followed by fixed (30.8%), and partially fixed (7.7%). Dermoid rigidity was most commonly described as firm (75.5%), followed by cystic, soft, and rubbery. The most common dermoid location was superotemporal (60.4%). On Chi-squared analysis, superotemporal lesions were less likely to have orbital extension than non-superotemporal lesions (OR 0.28, 95% CI: 0.11–0.70, p = .01), less likely to undergo CT (OR 0.16, 95% CI: 0.06–0.41, p < .01) or MRI (OR 0.23, 95% CI: 0.13–0.41, p < .01), more likely to be described as mobile (OR 2.91, 95% CI: 1.32–6.43, p = .01), and less likely to rupture intraoperatively (OR 0.28, 95% CI: 0.11–0.73, p = .01). No variables were associated with rupture in multivariate analysis. Conclusion: Superotemporal dermoid cysts are common in the pediatric population, less likely to have orbital extension, undergo imaging, and have intraoperative rupture when compared to other locations in the orbit.