Comparison and evolution of transcranial versus endoscopic endonasal approaches for suprasellar Meningiomas: A systematic review. (May 2022)

• Record Type: Journal Article
• Authors: Jimenez, Adrian E.; Harrison Snyder, M.; Rabinovich, Emily P.; Malkawi, Dima; Chakravarti, Sachiv; Wei, Oren; Cheshire, Madeline; Carrie Price, M.L.S.; Khalafallah, Adham M.; Rowan, Nicholas R.; Mukherjee, Debraj
• Is Part Of: Journal of clinical neuroscience. Volume 99(2022)
• Page Start: 302
• Page End: 310
• Publication Date: 2022-05
• Subjects: Meningioma -- Endoscopic surgical procedures -- Minimally invasive surgical procedures -- Skull base neoplasms -- Central nervous system neoplasms; Brain -- Surgery -- Periodicals; Neurosciences -- Periodicals; Nervous system -- Surgery -- Periodicals; Brain -- surgery -- Periodicals; Neurosurgical Procedures -- Periodicals; Neurosciences -- Periodicals; Electronic journals; 616.8
• DOI: 10.1016/j.jocn.2022.03.029
• Languages: English
• ISSNs: 0967-5868

Abstract

Highlights: Suprasellar meningiomas represent a unique challenge given their anatomic location. Suprasellar lesions are associated with high rates of visual disturbance. Endoscopic endonasal approach may maximize visual outcomes. Endoscopic endonasal approach is associated with significantly higher rates of cerebrospinal fluid leaks. Endoscopic endonasal approach offers a viable alternative to transcranial approach. Abstract: Background: Meningiomas of the tuberculum sellae (TS) and planum sphenoidale (PS) are challenging to treat surgically. Transcranial approaches (TCAs) were the mainstay before endoscopic endonasal approaches (EEA) were developed, however the efficacy and safety of EEA approaches relative to TCA approaches remains unclear. Methods: The authors conducted a PRISMA-compliant systematic review of existing literature detailing the outcomes of both approaches. PubMed, Embase, Cochrane Library, and Clinicaltrials.gov were searched. Studies were included if they analyzed TS and/or PS meningiomas, included ≥ 5 patients, and reported at least one outcome of interest. Results: Overall, 44 retrospective studies met inclusion criteria, the majority being from single centers, between 2004 and 2020. In studies directly comparing postoperative outcomes among TCA and EEA approaches, EEA had significantly higher odds of visual improvement (OR = 3.24, p = 0.0053) and significantly higher odds of CSF leak (OR = 3.71, p = 0.0098) relative to TCA. Further, there were no significant differences between visual worsening (p = 0.17), complications (p = 0.51), and GTR rates (p = 0.30) for the two approaches. Meta-analysis demonstrated no significant association between nasoseptal flap (NSF) use and postoperative outcomes among EEA patients. There was also no significant association between study publication year and postoperative EEA outcomes. Conclusion: The present study demonstrates that EEA offers a viable alternative to TCA in the treatment of suprasellar meningiomas. In particular, EEA shows promise for superior visual outcomes, though postoperative CSF leaks are an important consideration among patients undergoing this approach.