Membrane Biochips. (December 2002)

• Record Type: Journal Article
• Authors: Fang, Ye; Frutos, Anthony G.; Webb, Brian; Hong, Yulong; Ferrie, Ann; Lai, Fang; Lahiri, Joydeep
• Is Part Of: Biotechniques. Volume 33(2002)Supplement 6
• Page Start: S62
• Page End: S65
• Publication Date: 2002-12
• Subjects: Biology, Experimental -- Periodicals; Molecular biology -- Periodicals; Medical technology -- Periodicals; Biology, Experimental; Medical technology; Molecular biology; Clinical Laboratory Techniques -- Periodicals; Research -- Periodicals; Medical Laboratory Science -- Periodicals; Periodicals; Electronic journals; 570
• DOI: 10.2144/dec02fang
• Languages: English
• ISSNs: 0736-6205

Abstract

Membrane-bound proteins represent the single most important class of drug targets. This article discusses the issues surrounding fabrication of membrane–protein microarrays by conventional robotic pin printing techniques. Ligand binding selectivity and specificity to G protein-coupled receptor (GPCR) microarrays are presented. The potential applications of these arrays for drug screening are discussed.