A Case of Anti-SAE1 Dermatomyositis. (4th March 2022)

• Record Type: Journal Article
• Authors: de Vries, Max; Schreurs, Marco W. J.; Ahsmann, Els J. M.; Spee-Dropkova, Marcela; Karim, Faiz
• Other Names: Litzman Jiri Academic Editor.
• Is Part Of: Case reports in immunology. Volume 2022(2022)
• Publication Date: 2022-03-04
• Subjects: Immunology -- Periodicals; Immunology -- Case studies -- Periodicals; Immune System Phenomena; Immunology; Immunology; Case studies; Periodicals; 571.96
• DOI: 10.1155/2022/9000608
• Languages: English
• ISSNs: 2090-6609

Abstract

Abstract : Introduction . Anti-SAE1 antibodies have a low prevalence in dermatomyositis patients. Case Description . A 61-year-old woman presented with progressive shortness of breath, arthralgia, heliotrope rash, Gottron's papules, and erythematous rash. She had an interstitial lung disease (ILD) with a significant decrease in lung function. There was no muscle involvement. Immunological laboratory test results showed strongly positive anti-SAE1 antibodies. Glucocorticoid treatment resulted in remission of dermatomyositis. Conclusion . Anti-SAE antibodies in dermatomyositis patients are closely linked to unique clinical features.