Outcomes Associated With Antimicrobial De-escalation of Treatment for Pneumonia Within the Veterans Healthcare Administration. (10th December 2016)

• Record Type: Journal Article
• Authors: Bohan, Jefferson G.; Remington, Richard; Jones, Makoto; Samore, Matthew; Madaras-Kelly, Karl
• Is Part Of: Open forum infectious diseases. Volume 4:Number 1(2017)
• Publication Date: 2016-12-10
• Subjects: antimicrobial stewardship -- de-escalation -- outcomes -- pneumonia; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofw244
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: De-escalation, an antimicrobial stewardship concept, involves narrowing broad-spectrum empiric antimicrobial therapy based on clinical data. Current health outcomes evidence is lacking to support de-escalation. Studying Veterans Healthcare Administration pneumonia patients, de-escalation was associated with improved length of stay without affecting 30-day readmission or 30-day Clostridium difficile infection rates.