Coinfection by Aspergillus and Mucoraceae Species in Two Cases of Acute Rhinosinusitis as a Complication of COVID-19. (14th March 2022)

• Record Type: Journal Article
• Authors: Tabarsi, Payam; Sharifynia, Somayeh; Pourabdollah Toutkaboni, Mihan; Abtahian, Zahra; Rahdar, Mohammad; Mirahmadian, Arefeh Sadat; Hakamifard, Atousa
• Other Names: Cesaro Simone Academic Editor.
• Is Part Of: Case reports in medicine. Volume 2022(2022)
• Publication Date: 2022-03-14
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Case Reports; Periodicals; 610
• DOI: 10.1155/2022/8114388
• Languages: English
• ISSNs: 1687-9627

Abstract

Abstract : Acute invasive fungal rhinosinusitis (AIFR) is a life-threatening infection often found in immunocompromised patients. In the COVID-19 era, reports of AIFR have emerged, with high mortality and morbidity rate. This paper presents two cases of COVID-19 associated AIFR with the combined proven fungal etiology of Aspergillus flavus and Rhizopus arrhizus in case 1 and Aspergillus fumigatus and Rhizopus arrhizus in case 2. Both patients received liposomal amphotericin B then posaconazole combined with aggressive surgical debridement of necrotic tissues with a favorable clinical outcome. Mixed etiology AIFR can influence the outcome; hence, further studies are required upon this new threat.