Mechanism of Spindle Pole Organization and Instability in Human Oocytes. Issue 5 (May 2022)

• Record Type: Journal Article
• Authors: So, Chun; Menelaou, Katerina; Uraji, Julia; Harasimov, Katarina; Steyer, Anna M.; Seres, K. Bianka; Bucevičius, Jonas; Lukinavičius, Gražvydas; Möbius, Wiebke; Sibold, Claus; Tandler-Schneider, Andreas; Eckel, Heike; Moltrecht, Rüdiger; Blayney, Martyn; Elder, Kay; Schuh, Melina
• Is Part Of: Obstetrical & gynecological survey. Volume 77:Issue 5(2022)
• Page Start: 278
• Page End: 280
• Publication Date: 2022-05
• Subjects: Obstetrics -- Periodicals; Gynecology -- Periodicals; Generative organs, Female -- Surgery -- Periodicals; 618
• DOI: 10.1097/OGX.0000000000001038
• Languages: English
• ISSNs: 0029-7828

Abstract

Abstract : (Abstracted from Science 2022;375:eabj3944) Approximately 25% to 50% of human eggs are aneuploid, with even higher rates among older women. Aneuploidy is a leading cause of abnormal embryonic development resulting in miscarriage and genetic disorders.