Treatment of Dysplasia Epiphysealis Hemimelica with Autologous Chondrocyte Implantation: A Case Report. Issue 2 (4th April 2022)

• Record Type: Journal Article
• Authors: Bacon, Adam; Delman, Connor M.; Reynolds, James Phillip; Haus, Brian
• Is Part Of: JBJS case connector. Volume 12:Issue 2(2022)
• Publication Date: 2022-04-04
• Subjects: pediatric -- autologous chondrocyte implantation -- Trevor's disease -- dysplasia epiphysealis hemimelic -- distal femur -- ACI; Orthopedic surgery -- Case studies -- Periodicals; Orthopedic surgery -- Periodicals; Orthopedics; Orthopedic Procedures; Orthopedic surgery; Periodicals; Electronic journals; Case studies; Periodicals; 616.7
• DOI: 10.2106/JBJS.CC.21.00668
• Languages: English
• ISSNs: 2160-3251

Abstract

Abstract : Case: We present a case of dysplasia epiphysealis hemimelica (DEH) involving the posteromedial distal femur in a 4-year-old girl. The patient underwent lesion resection with internal fixation of the articular cartilage followed by autologous chondrocyte implantation (ACI) to restore the articular surface and epiphysis. At the 7-year follow-up, the patient had no pain or difficulty with participation in sports. Advanced imaging showed a stable articular surface with evidence of durable cartilage integration. Conclusion: DEH is a rare disease often treated by resection. In cases where the articular surface of the knee is involved, we have demonstrated that augmentation with ACI can be an effective treatment option.