Systemic antineutrophil cytoplasmic antibody vasculitis associated with lymphoid neoplasia. Issue 3 (1st March 2001)

• Record Type: Journal Article
• Authors: Hamidou, M A; El Kouri, D; Audrain, M; Grolleau, J-Y
• Is Part Of: Annals of the rheumatic diseases. Volume 60:Issue 3(2001)
• Page Start: 293
• Page End: 295
• Publication Date: 2001-03-01
• Subjects: vasculitis -- antineutrophil cytoplasmic antibodies -- chronic lymphocytic leukaemia -- lymphoma; Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/ard.60.3.293
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Two cases of systemic antineutrophil cytoplasmic antibody (ANCA) vasculitis in the setting of chronic lymphocytic leukaemia and angioimmunoblastic lymphadenopathy type T cell lymphoma are reported. The two patients had fever of unknown origin associated with cutaneous vasculitis and "pulmonary-renal syndrome" with alveolar haemorrhage. Despite anti-infectious treatments, steroids, and chemotherapy, the vasculitis had a fatal paraneoplastic course in several weeks. When infection is excluded in patients with malignancy, atypical features should be promptly investigated for systemic vasculitis, and an ANCA test performed.