Hypoparathyroidism and hypocalcaemia during treatment for acute leukaemia. Issue 6317 (6th March 1982)

• Record Type: Journal Article
• Authors: Freedman, D B; Shannon, M; Dandona, P; Prentice, H G; Hoffbrand, A V
• Is Part Of: BMJ. Volume 284:Issue 6317(1982)
• Page Start: 700
• Page End: 702
• Publication Date: 1982-03-06
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610
• DOI: 10.1136/bmj.284.6317.700
• Languages: English
• ISSNs: 0007-1447

Abstract

Abstract : Nine patients with acute leukaemia developed a complex syndrome of hypocalcaemia and hypomagnesaemia during treatment. These metabolic abnormalities developed rapidly in some patients and gave rise to acute symptoms. Immunoreactive parathormone concentrations in these patients were found to be either absolutely or inappropriately low. Hypomagnesaemia and the action of chemotherapeutic agents, especially adriamycin or cytarabine, or both may have contributed to the pathogenesis of this syndrome.