Intrahepatic persistent fetal right umbilical vein: a retrospective study. (17th December 2021)

• Record Type: Journal Article
• Authors: Toscano, Paolo; Saccone, Gabriele; Di Meglio, Lavinia; Di Meglio, Letizia; Mastantuoni, Enrica; Riccardi, Carla; Raffone, Antonio; Zullo, Fulvio; Locci, Mariavittoria; Di Meglio, Aniello
• Is Part Of: Journal of maternal-fetal & neonatal medicine. Volume 34:Number 24(2021)
• Page Start: 4025
• Page End: 4028
• Publication Date: 2021-12-17
• Subjects: Abortion -- fetal malformation -- genetic -- MRI -- NIPT; Obstetrics -- Periodicals; Perinatology -- Periodicals; Infants (Newborn) -- Diseases -- Periodicals; Neonatology -- Periodicals; 618.2
• DOI: 10.1080/14767058.2019.1702954
• Languages: English
• ISSNs: 1476-7058

Abstract

Abstract: Introduction: To appraise the incidence and value of intrahepatic persistent right umbilical vein (PRUV). Methods: This was a single-center study. Records of all women with a prenatal diagnosis of intrahepatic PRUV were reviewed. The inclusion criteria were women with gestational age greater than 13 weeks of gestation. Exclusion criteria were fetuses with situs abnormalities, due to the hepatic venous ambiguity, and extrahepatic PRUV. The primary outcome was the incidence of intrahepatic PRUV in our cohort. The secondary outcomes were associated malformations. Results: 219/57, 079 cases (0.38%) of intrahepatic PRUV were recorded. The mean gestational age at diagnosis was 21.8 ± 2.9 weeks of gestations. PRUV was isolated in the 76.7%, while in 23.3% was associated with other major or minor abnormalities. The most common associated abnormalities were cardiovascular abnormalities (8.7%), followed by genitourinary abnormalities (6.4%), skeletal abnormalities (4.6%), and central nervous system abnormalities (4.1%). Within the cardiovascular abnormalities, the most common one was ventricular septal defect (six cases). Conclusion: In most cases PRUV is an isolated finding. Associated minor or major malformations are presented in the 23.3% of the cases, so this finding should prompt detailed prenatal assessment of the fetus, with particular regard to cardiovascular system.