SAT0649 Correlation between clinical manifestations and 18f-fdg uptake in patients with polymyalgia rheumatica. (12th June 2018)

• Record Type: Journal Article
• Authors: Prieto-Peña, D.; Loricera, J.; Martínez-Rodríguez, I.; Banzo, J.; Calderón-Goercke, M.; Calvo-Río, V.; González-Vela, C.; González-Gay, M.; Hernández, J.; Blanco, R.
• Is Part Of: Annals of the rheumatic diseases. Volume 77(2018)Supplement 2
• Page Start: 1174
• Page End: 1175
• Publication Date: 2018-06-12
• Subjects: Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/annrheumdis-2018-eular.4968
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Background: Polymyalgia rheumatica (PMR) is an inflammatory disease characterised by pain and stiffness of the neck, shoulder and pelvic girdles. It can also be accompanied by other non-specific symptoms such as inflammatory low back pain, diffuse lower limb pain and constitutional syndrome. The role of 18 F-FDG PET/CT is increasing in the diagnosis of PMR but it remains unknown if there is a correlation between clinical symptoms and 18 F-FDG uptake. Objectives: Our aim was to asses if the localization of pain of patients with PMR correlates with 18 F-FDG uptake in the corresponding region of interest. Methods: Retrospective study of 75 patients with PMR and their respective PET/CT scans from a referral centre. PMR diagnosis was based on 2012 EULAR/ACR criteria. Results: We evaluated 75 patients (27 men and 48 women) with a mean age ±SD of 68.2±10.7 years. A PET/CT was performed in all of them. Pattern of F-FDG uptake in patients with different clinical manifestations were summarised in the TABLE . Twenty-two out of thirty-three patients (66.7%) with 18 F-FDG uptake in sternoclavicular joints had shoulder girdle pain. In all patients with morning stiffness (n=11) an increase of 18 F-FDG uptake in shoulders was observed. Twenty-three patients of thirty-two patients (71.8%) with 18 F-FDG uptake in hips had pelvic girdle pain. The remaining localizations of 18 F-FDG uptake in PET/CT scans did not show significant correlations with clinical symptoms. Conclusions: In patients with PMR, the presence of shoulder girdle pain seems to correlate with F- 18 FDG uptake in sternoclavicular joints, morning stiffness with 18 F-FDG uptake in shoulders and pelvic girdle pain with 18 FDG uptake in hips. No other significant correlations were found between any other symptom and 18 F-FDG uptake. Disclosure of Interest: None declared